Cast
Chris RockOsmosis Jones (voice)
Laurence FishburneThrax (voice)
David Hyde PierceDrix (voice)
Brandy NorwoodLeah (voice)
Elena FranklinShane Detorre
Bill MurrayFrank Detorre
William ShatnerMayor Phlegmming (voice)
Ron HowardTom Colonic (voice)
Kid RockKidney Rock (voice)
Molly ShannonMrs. Boyd
Chris ElliottBob
Jonathan AdamsOfficer Tom (voice)
Carlos AlazraquiSpanish Germ (voice)
Keith AnthonyAdditional Character Voices (voice)
Eddie BarthConductor (voice)
